(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Tert-Butyl Ester

(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Tert-Butyl Ester - Names and Identifiers

Name	(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Tert-Butyl Ester
Synonyms	α-(Boc-aMino)phenethylaMine alpha-(Boc-amino)phenethylamine 2-(Boc-amino)-2-phenylethylamine tert-Butyl (2-amino-1-phenylethyl)carbamate tert-Butyl N-(2-amino-1-phenylethyl)carbamate 1,1-Dimethylethyl (2-amino-1-phenylethyl)carbamate 2-Methyl-2-propanyl-(2-amino-1-phenylethyl)carbamat 2-Methyl-2-propanyl (2-amino-1-phenylethyl)carbamate (2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Tert-Butyl Ester (2-AMINO-1-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER CarbaMic acid, N-(2-aMino-1-phenylethyl)-, 1,1-diMethylethyl ester Carbamic acid, N-(2-amino-1-phenylethyl)-, 1,1-dimethylethyl ester
CAS	142910-85-8
InChI	InChI=1/C13H20N2O2/c1-13(2,3)17-12(16)15-11(9-14)10-7-5-4-6-8-10/h4-8,11H,9,14H2,1-3H3,(H,15,16)

(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Tert-Butyl Ester - Physico-chemical Properties

Molecular Formula	C13H20N2O2
Molar Mass	236.31
Density	1.066±0.06 g/cm3(Predicted)
Melting Point	85-90°C
Boling Point	372.2±35.0 °C(Predicted)
Flash Point	178.903°C
Vapor Presure	0mmHg at 25°C
pKa	11?+-.0.46(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.524
MDL	MFCD09027881

(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Tert-Butyl Ester - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
WGK Germany	3

(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Tert-Butyl Ester - Introduction

tert-Butyl N-(2-amino-1-phenylethyl) carbamate, often abbreviated as Boc-β-alanine, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless or white crystalline powder
-Molecular formula: C14H22N2O4
-Molecular weight: 286.34g/mol
-Melting point: 89-92 ℃
-Soluble: Soluble in ethanol, ether and dimethyl sulfoxide

Use:
- Boc-β-alanine is commonly used as a protecting group in organic synthesis to protect the amino functional group of compounds such as amino acids and peptides.
-It can also be used as a pharmaceutical intermediate for the synthesis of biologically active compounds.
-In addition, Boc-β-alanine can also be used in the fields of protein engineering and peptide synthesis.

Preparation Method:
The preparation of Boc-β-alanine typically involves the following steps:
1. Condensation reaction of 2-amino-1-phenylethanol and tert-butyl formate to obtain N-(2-amino-1-phenylethyl) carbamic acid;
2. Ethylating the resulting product to obtain the final product Boc-β-alanine.

Safety Information:
- Boc-β-alanine is considered safe under routine experimental conditions.
-But it may be irritating to the skin and eyes, so appropriate protective measures should be taken when handling it.
-Avoid contact with oxidants and acids during use and storage.

Please note that for the specific use and preparation conditions of chemical substances, you should also carefully refer to relevant literature and experimental methods.

Last Update：2024-04-09 20:52:54